Micreos Human Health develops targeted antibacterial products for human health based on its endolysin technology.
In 2013 the company introduced the world's first series of endolysin-based products for human health. Launched under the Gladskin brand, in 2019 alone these products have helped over 100,000 people with inflammatory skin conditions such as eczema, inflammatory acne, rosacea and psoriasis. The endolysin Staphefekt SA.100, the active ingredient in these Gladskin products, specifically targets S. aureus, including the resistant MRSA. S. aureus causes the majority of all bacterial skin infections and aggravates many skin conditions. The Gladskin products are prescription-free, suitable for daily use as long as needed and available in Europe and an increasing number of other countries. The introduction of Gladskin in the USA is planned in January 2020.
In 2018 Erasmus Medical Centre finished a randomised controlled trial with Gladskin Eczema, confirming a favorable safety profile. Further trials of Gladskin products are ongoing, including a non-randomised trial among patients with primary immune deficiencies.
The company's proprietary endolysin XZ.700 is in clinical development for registration as a pharmaceutical product for various indications. XZ.700 specifically kills S. aureus, now established as a major trigger for flares in eczema. Atopic Dermatitis is the first targeted XZ.700 indication. Non-clinical studies are ongoing in preparation of a combined Phase I/IIa trial, scheduled to start in 2020. Details on the company's clinical development program are available upon request.
In October 2014 Micreos also introduced Staphefekt XDR.300, a liquid solution against S. aureus including MRSA.
Our pipeline also includes products against intracellular Staph and against other bacterial species
|
Latest fact sheets on: |
|
Staphylococcus aureus |
Micreos Staphefekt SA.100 |
 Download |
|
Colonization Infection Continuum |
Micreos Staphefekt SA.100 |
Download |
|
Eczema |
Micreos Staphefekt SA. 100 (Gladskin) |
Download |
|
Rosacea |
Micreos Staphefekt SA.100 (Gladskin) |
Download |
|
Acne |
Micreos Staphefekt SA.100 (Gladskin) |
Download |
|
Folliculitis/Furunculosis |
Micreos Staphefekt SA.100 (Gladskin) |
Download |
For inquiries or partnerships, please contact us at: info@micreos.com