Help us to build the world's best Biotechnology company focused on the great unmet Medical need of Anti-Microbial Resistance (AMR)?
Micreos Pharma is a highly innovative, fully fledged, biotechnology company focused on the targeted killing of bacterial pathogens (that harms human health) while protecting the rest of the Microbiome (that promotes good human health).
We are now looking for a Scientist Drug Substance Development (DSD).
Your role at Micreos
As a Scientist Drug Substance (DS) Development, you contribute to the successful setup, development, qualification and validation of endolysin-based products (including DS related activities outsourced to contractors). You participate in the design and coordination of DS development, product characterization, range finding (DoE) and troubleshooting studies. You contribute to the development of MHH as a centre of excellence for endolysin-based production.
Main objectives of the role
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Setup, execute and timely report process development and characterization activities.
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Contribute to the design and coordination of drug substance development activities, working closely together with the other drug substance scientists and technicians.
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Coordinate in house development and outsourcing activities for drug substance development.
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Contribute to the professionalisation of the Development organisation, focusing on data integrity and scientific soundness
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Report to the Drug Substance Development Lead and collaborate with the Drug Product development team and the Analytical Development Team, all part of the CMC group at Micreos Bilthoven.
More about you and your competences
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At least 2 years’ experience in early stage or mid stage drug substance development (additional analytical development experience is a plus) in an industrial environment.
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Knowledge regarding Good Manufacturing Practice requirements is a must.
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Experience with QbD and risk assessments is preferred.
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MSc degree in Biopharmaceutical sciences, Biochemistry or Biotechnology (PhD preferred)
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Experience with two or more of the following: Regulatory submission writing, DoE and general statistical methods (e.g., Multivariate Data Analysis, Data trending), technology transfer
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Team player
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Strong scientific mind-set
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Passion, initiative and creative
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Problem solving attitude
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Pro-active, self-starter, “can do”attitude
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Fluent in English (both written and spoken)
Our offer
Micreos offers a varied full time role within a young and enthusiastic team. The salary offered is in line with market conditions and you will be given the opportunity to make the fullest use of your talents. We offer you an ambitious and pleasant international working environment.
Is this the role you are looking for?
Our Micreos HR team is looking forward to receiving your CV and cover letter via recruitment@micreos.com. Any questions regarding the role can also be addressed to this email address.
Please only apply if you are eligible to work in the Netherlands.
Company profile Micreos Pharma:
Bacteria are all around us. Some of them are good and provide health benefits, but many can cause irritation or infection. It has become evident that our microbiome, comprising OF billions of beneficial bacteria, is necessary for our well being and should where possible be left intact. Traditional Antibiotics do not distinguish between good and bad bacteria and their overuse can lead to side effects and resistance which has the potential to cause significant issues for mankind. The emergence of the so called ‘antibiotic-resistant superbugs' is now of global concern.
Micreos develops the world's first targeted antibacterial products that are now being studied in a number of medical indications. The company is viewed as global leader spearheading this exciting new field. With Micreos endolysin technology, for the first time we can selectively kill only the unwanted bacteria - including antibiotic resistant strains - while leaving the beneficial bacteria intact. In addition, research shows that the use of endolysins does not induce resistance which potentially makes them suitable for longer term use in chronic conditions. This unlocks a completely new approach to dealing with the bacteria around us, enabling daily use while preserving the important biodiversity on our skin and in our gut.
This is an exciting time to join Micreos Pharma to improve standards of care for patients in select indications in dermatology and oncology.
Acquisitions following this vacancy are not appreciated.